Denovo High Grade Salivary
Duct Carcinoma: A Case Report
and Review of Literature
Published: July 1, 2017 | DOI: https://doi.org/10.7860/JCDR/2017/29195.10210
Heena Zainab, Ameena Sultana, Pramod Jahagirdar
1. Professor and Head, Department of Oral and Maxillofacial Pathology and Microbiology, Al Badar Rural Dental College and Hospital, Kalaburgi, Karnataka, India.
2. Postgraduate Student, Department of Oral and Maxillofacial Pathology and Microbiology, Al Badar Rural Dental College and Hospital, Kalaburgi, Karnataka, India.
3. Professor, Department of Oral and Maxillofacial Pathology and Microbiology, Al Badar Rural Dental College and Hospital, Kalaburgi, Karnataka, India.
Correspondence
Dr. Heena Zainab
Professor and Head, Department of Oral and Maxillofacial Pathology and Microbiology,
Al Badar Rural Dental College and Hospital, Kalaburgi-585102, Karnataka, India.
E-mail: hinazainab1@yahoo.co.in
Salivary Duct Carcinoma (SDC) is a distinctive and clinically aggressive adenocarcinoma of salivary origin. It arises from the ductal epithelium, predominantly occurring in the major salivary glands, especially the parotid gland. Here, we report a case of an extensive salivary gland pathology involving the right side of face, possibly arising from the parotid gland in a 25-year-old male patient. On routine histopathology, the tumour mass revealed a papillary pattern of neoplastic ductal epithelial cells showing comedo-like-central necrosis. Immunohistochemical staining showed tumour cells in the infiltrative component to be diffusely immunopositive for cytokeratin-7 and Her-2, confirming the diagnosis of SDC. This paper presents a case report on salivary duct carcinoma and highlights a review on histological variants of salivary duct carcinoma.
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